In the Rogue Valley, you might sneak into New Sammy's Cowboy Bistro,
here in Talent-
2210 S. Pacific Highway
Talent 541-535-2779
Great Wine knowledge and selection, home grown vegetables, no sign.
Our Farmer's markets are on Tuesday and Thursday-
http://roguevalleygrowersandcraftersmarket.com/
Our friends Marco and Elise have just opened Inti- a Latin Taco Place,
in Downtown Talent.
They'd love to see you.
Lots of local food producers & places to eat
Dagoba
Rogue Creamery for Blue Cheese!
http://www.roguecreamery.com
Peerless on 4th Street.
Omar's.
Wiley's Pastas.
Apple Cellar Bakery.
Rising Sun Farms
http://www.risingsunfarms.com/pilot.asp?pg=retail_store
Here's an overview of some local places:
http://www.atasteofashland.com/commerce/diningpage.html
On routing:
If you can make it beyond Crescent City to Brookings or Gold Beach,
for the night, It'd be worth your while.
At each small town, you need to find the harbor, and you'll find the seafood, either being hauled in, processed, or cooked.
If you continue up the Coast, make sure to make your way from Bandon out to Charleston. Elegant to
Funky & real.
For a more foodcentric route, I'd have you turn in on US199, hit Jed Smith State Park, (better groves than the National Park), then Oregon-
You've got the Treehouses in Takilma,
http://www.treehouses.com/
Taylor's Sausages
http://www.wendyhuber.com/taylors/index.html
in Cave Junction, The Caves themselves + 3 wineries out that a ways.
If you came in to Grants Pass, then come the back way to Jacksonville through the Applegate, home of several small wineries.
The rim road at Crater Lake just opened for the summer too. Something to think about, because then you could hit the Pinehurst Inn-
http://www.pinehurstinn.us
or the Greensprings Inn
http://www.greenspringsinn.net
both in the high country
Here's our SO wine link-
http://www.sorwa.org/
There's also, if you're an explorer, a really cool Forest service road, Bear Camp Road, that follows the Rogue from Gold Beach to Galice.
It's worth writing home about.
http://www.goldbeach.net/maps.htm
Favorite place between here and Redding is Sengthong's Asian Cuisine in Dunsmuir, open only evenings.
http://www.dunsmuir.com/busguide.htm#dining
Several places in Mt. Shasta too.
Klub Klondike at Lakehead on the East side of I-5 is a cool Bar & snack stop complete with Retired country musician & wife owners and a shuffleboard machine W/chalk.
Bartel's in Redding and Corning for the best hamburgers.
The Olive Pit in Corning & Granzella's in Williams for local Olives and Rice,
and a beer, and you're almost to Sacramento and the Airport.
In my travels round this region, if you allow 75-150 miles, it'll yield maximum results. And remember, it's easy to get here, it's just hard to leave.